FURTHER EXPERIENCES WITH PICROTOXIN AS A CONVULSANT IN THE TREATMENT OF MENTAL ILLNESSES
ABRAHAM A. LOW M. D.1,
ELIZABETH MACDOUGALL M. D.1,
EDWARD ROSS M. D.1,
MANDEL SACHS M. D.1, , and
DAVID LEVITIN M. D.1
1 The Psychiatric Institute (H. Douglas Singer, Director) of the Research and Educational Hospitals, the University of Illinois College of Medicine.
1. A report is given of 102 patients treated with picrotoxin as convulsant. 64 of the patients received a combination of picrotoxin with metrazol.
2. The combined treatment reduces nausea and vomiting to a minimum. Multiple convulsions occurred in two instances only. Terror was absent, and the paroxysm was induced in a conveniently short time.
3. Complications were approximately the same in type and frequency as when picrotoxin or metrazol alone were used.