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Am J Psychiatry 97:686-690, November 1940
doi: 10.1176/appi.ajp.97.3.686
© 1940 American Psychiatric Association
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FURTHER EXPERIENCES WITH PICROTOXIN AS A CONVULSANT IN THE TREATMENT OF MENTAL ILLNESSES

ABRAHAM A. LOW M. D.1, ELIZABETH MACDOUGALL M. D.1, EDWARD ROSS M. D.1, MANDEL SACHS M. D.1, , and DAVID LEVITIN M. D.1

1 The Psychiatric Institute (H. Douglas Singer, Director) of the Research and Educational Hospitals, the University of Illinois College of Medicine.

1. A report is given of 102 patients treated with picrotoxin as convulsant. 64 of the patients received a combination of picrotoxin with metrazol.

2. The combined treatment reduces nausea and vomiting to a minimum. Multiple convulsions occurred in two instances only. Terror was absent, and the paroxysm was induced in a conveniently short time.

3. Complications were approximately the same in type and frequency as when picrotoxin or metrazol alone were used.







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