Am J Psychiatry 155:548-551, April 1998
© 1998 American Psychiatric Association
Does Fluoxetine Augment the Inpatient Treatment of Anorexia Nervosa?
Evelyn Attia, M.D.,
Claire Haiman, B.A.,
B. Timothy Walsh, M.D., and
Susanne R. Flater, R.N., C.
OBJECTIVE: While pharmacological interventions are of established utility in bulimia nervosa, medications have no clear role in the treatment of anorexia nervosa. Because patients with anorexia nervosa frequently exhibit mood disturbances and symptoms of obsessive-compulsive disorder, the authors tested the utility of fluoxetine in the treatment of women participating in an inpatient program for anorexia nervosa. METHOD: The authors conducted a randomized, placebo-controlled, double-blind, 7-week study of fluoxetine at a target daily dose of 60 mg in 31 women with anorexia nervosa receiving treatment for their eating disorder on a clinical research unit. Body weight and measures of eating behavior and psychological state were obtained at baseline and at termination. RESULTS: There were no significant differences in clinical outcome on any measure between patients receiving fluoxetine and patients receiving placebo. CONCLUSIONS: Fluoxetine does not appear to add significant benefit to the inpatient treatment of anorexia nervosa.
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References
PsychiatryOnline CME,
May 1, 2007;
2007(1):
2 - 2.
[Full Text]
|
|
|
|
|
|
|
B. T. Walsh, A. S. Kaplan, E. Attia, M. Olmsted, M. Parides, J. C. Carter, K. M. Pike, M. J. Devlin, B. Woodside, C. A. Roberto, et al.
Fluoxetine after weight restoration in anorexia nervosa: a randomized controlled trial.
JAMA,
June 14, 2006;
295(22):
2605 - 2612.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. J. Crow
Fluoxetine treatment of anorexia nervosa: important but disappointing results.
JAMA,
June 14, 2006;
295(22):
2659 - 2660.
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Yager and A. E. Andersen
Anorexia Nervosa
N. Engl. J. Med.,
October 6, 2005;
353(14):
1481 - 1488.
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Yager, M. J. Devlin, K. A. Halmi, D. B. Herzog, J. E. Mitchell, P. S. Powers, and K. J. Zerbe
Eating Disorders
Focus,
October 1, 2005;
3(4):
503 - 510.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Royal Australian and New Zealand College of Psychi
Australian and New Zealand Clinical Practice Guidelines for the Treatment of Anorexia Nervosa
Focus,
October 1, 2005;
3(4):
618 - 628.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. Sysko, B T. Walsh, J. Schebendach, and G T. Wilson
Eating behavior among women with anorexia nervosa
Am. J. Clinical Nutrition,
August 1, 2005;
82(2):
296 - 301.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. Bergh, U. Brodin, G. Lindberg, and P. Sodersten
Randomized controlled trial of a treatment for anorexia and bulimia nervosa
PNAS,
July 9, 2002;
99(14):
9486 - 9491.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. Mayer
Body composition and anorexia nervosa: does physiology explain psychology?
Am. J. Clinical Nutrition,
May 1, 2001;
73(5):
851 - 852.
[Full Text]
[PDF]
|
|
|
|
|
|
|
Fluoxetine for Malnourished Anorexic Patients?
Journal Watch Psychiatry,
June 1, 1998;
1998(601):
8 - 8.
[Full Text]
|
|
|
|
|
|
|
B. T. Walsh and M. J. Devlin
Eating Disorders: Progress and Problems
Science,
May 29, 1998;
280(5368):
1387 - 1390.
[Abstract]
[Full Text]
|
|
|
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