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Am J Psychiatry 1992; 149:671-675
Copyright © 1992 by American Psychiatric Association
Posttraumatic stress disorder in an urban population of young adults: risk factors for chronicity
N Breslau and GC Davis
Department of Psychiatry, Henry Ford Hospital, Detroit, MI 48202-2689.
OBJECTIVE: Despite progress in epidemiologic research on posttraumatic
stress disorder (PTSD), little is known about factors that distinguish
chronic from nonchronic PTSD. In a previous report, the authors identified
a set of personal predispositions associated with PTSD following traumatic
events in a general population sample of young adults. The purpose of this
analysis was to identify characteristics of chronic PTSD and examine
whether any of the suspected risk factors for PTSD was associated
specifically with chronic PTSD. METHOD: A random sample of 1,007 21- to
30-year-old members of a large health maintenance organization in the
Detroit area was interviewed, using the National Institute of Mental Health
Diagnostic Interview Schedule (DIS), revised for DSM-III-R. The analysis
was performed on data from 394 respondents who reported traumatic events,
of whom 93 met criteria for PTSD. Chronic PTSD was defined as duration of
symptoms for 1 year or more. RESULTS: Persons with chronic PTSD (N = 53)
had, on the average, a significantly higher total number of PTSD symptoms
and higher rates of overreactivity to stimuli that symbolized the stressor
and interpersonal numbing than persons with nonchronic PTSD. The rates of
one or more additional anxiety or affective disorders and a variety of
medical conditions were higher in persons with chronic than nonchronic
PTSD. Family history of antisocial behavior and female sex were associated
specifically with chronic PTSD. CONCLUSIONS: The findings suggest that
chronic PTSD may be associated with specific risk factors and clinical
features. Longitudinal data on the course of PTSD are needed to determine
whether the distinct features and the medical and psychiatric histories of
persons with chronic PTSD are complications attendant on a chronic course
or coexisting disturbances that inhibit recovery.
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