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Am J Psychiatry 1990; 147:492-494
Copyright © 1990 by American Psychiatric Association

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Trial of fluoxetine added to neuroleptics for treatment-resistant schizophrenic patients

DC Goff, AW Brotman, M Waites and S McCormick
Erich Lindemann Mental Health Center, Massachusetts General Hospital, Boston.

Mean ratings of positive and negative symptoms and depression significantly improved in nine treatment-resistant schizophrenic patients who completed a 6-week open trial of fluoxetine added to their neuroleptics. The authors identify differences between responders and nonresponders and recommend controlled trials.




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