Am J Psychiatry 1976; 133:82-85
Copyright © 1976 by American Psychiatric Association
Thioridazine and sexual dysfunction
J Kotin, DE Wilbert, D Verburg and SM Soldinger
The authors found a 60% incidence of difficulties in sexual functioning in
57 male patients who had taken thioridazine. Ejaculatory problems were the
most frequent dysfunction; a third of these patients experienced retrograde
ejaculation. The incidence of sexual difficulties in 64 patients who had
taken other major tranquilizers was only 25%. None of the latter group
experienced retrograde ejaculation- most had difficulty achieving and
maintaining erection. The authors recommend consideration of the
possibility of sexual dysfunction in patients given thioridazine.
