Am J Psychiatry 1975; 132:1325-1326
Copyright © 1975 by American Psychiatric Association
Blood pressure and pulse changes in hyperactive children treated with imipramine and methylphenidate
LM Greenberg and AM Yellin
The authors found significant increases in systolic and diastolic blood
pressure and pulse rate in hyperactive children treated with imipramine.
Methylphenidate-treated children showed significant weight loss but no
significant changes in blood pressure or pulse. The authors recommend
caution in the use of imipramine and suggest the need for further study to
determine short- and long-term effects of imipramine on blood pressure.
